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New Research on Cannabidiol for Epileptic Children

New research from the New England Journal of Medicine, outlines more evidence to support the effectiveness of cannabis to reduce seizures in epileptic children with Dravet syndrome.

Epilepsy is a neurological disease that causes various forms of seizures, ranging from undetectable to full-body convulsions. There are six main types of seizures associated with Epilepsy: clonic, tonic, tonic-clonic, myoclonic, absence and atonic seizures. According to the latest estimates, around 5.1 million children and adults in the US have had an epilepsy diagnosis or seizure disorder. The Dravet syndrome is a complex childhood epilepsy disorder that is associated with drug-resistant seizures and a high mortality rate.

This particular study was a double-blind, placebo-controlled trial, where 120 children and young adults with Dravet syndrome were randomly assigned cannabidiol or placebo. What they were measuring, was the change in convulsion-seizure frequency over a 14-week treatment period.

The median frequency of convulsive seizures per month decreased from 12.4 to 5.9 with cannabidiol, as compared with a decrease from 14.9 to 14.1 with placebo. The patient’s overall condition improved by at least one category on the seven-category Caregiver Global Impression of Change scale in 62% of the cannabidiol group as compared with 34% of the placebo group. [New England Journal of Medicine]

To hear a real story of someone we are working with, watch this mother talk about how 420 Clinic and medical cannabis are helping her epileptic son live a normal life for the first time.

 

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